HOW TO SOLVE PROTEIN CRYSTAL STRUCTURES?
DR. LEE'S RESOUCES FOR STRUCTURAL STUDIES
a) Synchrotron X-ray Source (National Synchrotron Light Source II at Brookhaven National Laboratory), b) In-house X-ray Source, c) High-throughput Crystallization Screening System (Crystal Gryphon, Art Robbins Instruments), d) Automatic Protein Crystal Imaging System (CrysCam Digital Microscope, Art Robbins Instruments)
FEATURED CRYSTAL STRUCTURES
PfPMT + SAH + pEA
PDB code: 5UJB
Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite
Plasmodium falciparum - an anti-parastic drug target. J Biol Chem 287, 1426-34
AtIPMDH2 + IPM
PDB code: 5J32
Structure and mechanism of isopropylmalate dehydrogenase from Arabdiopsis thaliana: insights on leucine and aliphatic glucosinolate biosynthesis
J Biol Chem 291, 13421-30
AtIPMDH2 + NAD
PDB code: 5J33
Structure and mechanism of isopropylmalate dehydrogenase from Arabdiopsis thaliana: insights on leucine and aliphatic glucosinolate biosynthesis
J Biol Chem 291, 13421-30
NolR + DNA
PDB code: 4OMY
Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR
Proc Natl Acad Sci USA 111, 6509-14
DR. LEE'S STRUCTURES IN PDB
